Purpose: To describe a method to center a Descemet stripping automated endothelial keratoplasty lamellar graft and address interface folds.
Methods: A novel technique to center a Descemet stripping automated endothelial keratoplasty graft without undue manipulation of endothelial surface using a STC-6 needle passed obliquely through the anterior corneal surface to engage and progress the lenticule along the posterior surface after injection of air.
Result: Centration of graft achieved and macroscopic folds resolved.
Conclusions: Here, we describe an atraumatic and reproducible method for graft centration.