Cis-diamminedichloroplatinum (II). A new anticance...[Ann Intern Med. 1977]

Search for

Advanced Search (beta)

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 1

Click to change filter selection through MyNCBI.

1: Ann Intern Med. 1977 Jun;86(6):803-12.Links

Cis-diamminedichloroplatinum (II). A new anticancer drug.

Rozencweig M, von Hoff DD, Slavik M, Muggia FM.

Cis-diamminedichloroplatinum (II) (DDP) leads the series of platinum coordination complexes, a new class of cytotoxic agents. The antitumor and toxic effects of this drug are discussed. It has displayed encouraging results in testicular tumors. The drug's therapeutic effectiveness has also been recognized in a variety of other solid tumors, particularly ovarian, bladder, and head and neck malignancies. Gastrointestinal, renal, audiologic, and relatively minor hematologic toxicities may be encountered, but promising methods have been developed to increase the therapeutic index of DDP.

PMID: 326117 [PubMed - indexed for MEDLINE]

Cis-platinum: a new anticancer agent. [Br Med J. 1979]
[Cis-diamminedichloroplatinum(II). A new antineoplastic agent derived from the group of heavy metal complexes (author's transl)] [Klin Wochenschr. 1979]
The role of cis-platinum in solid-tumor therapy. [N Engl J Med. 1979]
[First therapeutic experience with cis-platinum(II)diamindichloride (NSC 119875) in metastasizing ovarian and testicular carcinoma] [Schweiz Med Wochenschr. 1976]
[Phase II study on cis-diamminedichloroplatinum (II) by a collaborative study] [Gan To Kagaku Ryoho. 1982]
» See all Related Articles...

Patient Drug Information

Cisplatin (Platinol®-AQ) Your doctor has ordered the drug cisplatin to help treat your illness. The drug is given by injection into a vein.

» read more ...

Display Show

Cis-diamminedichloroplatinum (II). A new anticancer drug.

Related Articles