2019 Novel Coronavirus Pandemic: What Do We Know?

S D Med. 2020 Jun;73(6):262-264.

Abstract

The pandemic caused by SARS-COV2 Virus/COVID-19, which was initially reported in China in December 2019, has become a major global health concern. COVID-19 can manifest with cytokine storm - an exaggerated systemic inflammatory phenomenon due to over-production of proinflammatory cytokines by immune cells that results in diffuse inflammatory lung disease and acute respiratory distress syndrome. It may be complicated by septic shock and subsequent multi-organ failure. Based on the most recently published evidence, this article will review and discuss comprehensive information on its clinical manifestations, laboratory tests, potential therapeutics, and prevention guidelines.

Publication types

  • Review

MeSH terms

  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections / diagnosis*
  • Coronavirus Infections / prevention & control*
  • Coronavirus Infections / therapy*
  • Cytokine Release Syndrome / virology
  • Humans
  • Multiple Organ Failure / virology
  • Pandemics / prevention & control*
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / prevention & control*
  • Pneumonia, Viral / therapy*
  • Respiratory Distress Syndrome / virology
  • SARS-CoV-2
  • Shock, Septic / virology