A suspicious role of interferon in the pathogenesis of SARS-CoV-2 by enhancing expression of ACE2

Signal Transduct Target Ther. 2020 May 21;5(1):71. doi: 10.1038/s41392-020-0185-z.

Authors

Shan Su¹, Shibo Jiang²

Affiliations

¹ Key Laboratory of Medical Molecular Virology (MOE/MOH/CAM), School of Basic Medical Sciences, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai, 200032, China.
² Key Laboratory of Medical Molecular Virology (MOE/MOH/CAM), School of Basic Medical Sciences, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai, 200032, China. shibojiang@fudan.edu.cn.

No abstract available

MeSH terms

Angiotensin-Converting Enzyme 2
Betacoronavirus / genetics*
Betacoronavirus / pathogenicity
COVID-19
Coronavirus Infections / genetics*
Coronavirus Infections / virology
Gene Expression Regulation, Enzymologic / genetics
Humans
Interferons / genetics*
Pandemics
Peptidyl-Dipeptidase A / genetics*
Pneumonia, Viral / genetics*
Pneumonia, Viral / virology
SARS-CoV-2
Sequence Analysis, RNA
Signal Transduction / genetics
Single-Cell Analysis

Substances

Interferons
Peptidyl-Dipeptidase A
ACE2 protein, human
Angiotensin-Converting Enzyme 2