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    J Hypertens Suppl. 1988 Dec;6(4):S529-31.

    Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?

    Source

    Department of Clinical Pharmacology, Sahlgren's University Hospital, Gothenburg, Sweden.

    Abstract

    Muscle nerve sympathetic activity was recorded in six patients with the sleep apnoea syndrome (SAS). Compared with age- and sex-matched control patients, an increased activity during wakefulness was found. Sleep apnoic events were associated with sequencies of progressively increasing sympathetic activity followed by a sudden reduction of activity. The high sympathetic activity associated with SAS may be important in the development of the systemic hypertension commonly seen in these patients.

    PMID:
    3241251
    [PubMed - indexed for MEDLINE]

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