Effect of continuous postoperative epidural analgesia on intestinal motility

Br J Surg. 1988 Dec;75(12):1176-8. doi: 10.1002/bjs.1800751210.

Abstract

The effect of postoperative epidural bupivacaine on intestinal motility was studied by measuring the transit time of barium contrast through the intestines in 16 patients after resection of the left colon and/or rectum. Fourteen patients served as controls and received postoperative injections of pentazocine. Mean transit time through the intestinal tract was 35 h in the epidural group and 150 h in the control group, a difference that is significant at the 0.1 per cent level. The average time before passage of flatus and faeces was different between the two groups at the 0.1 per cent level. We conclude that postoperative epidural bupivacaine constitutes an effective means of analgesia after colorectal surgery and is associated with a short duration of intestinal paralysis.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Analgesia, Epidural*
  • Barium Sulfate
  • Bupivacaine / administration & dosage
  • Bupivacaine / therapeutic use*
  • Colon / surgery
  • Gastrointestinal Motility / drug effects*
  • Humans
  • Middle Aged
  • Pain, Postoperative / drug therapy*
  • Pentazocine / administration & dosage
  • Pentazocine / therapeutic use*
  • Rectum / surgery

Substances

  • Barium Sulfate
  • Pentazocine
  • Bupivacaine