Association Between Immigration Status and Acute Stroke Care: A Retrospective Study

Stroke. 2020 May;51(5):1555-1562. doi: 10.1161/STROKEAHA.119.027791. Epub 2020 Apr 13.

Abstract

Background and Purpose- Immigrants to high-income countries have a lower incidence of stroke compared with long-term residents; however, little is known about the care and outcomes of stroke in immigrants. Methods- We used linked clinical and administrative data to conduct a retrospective cohort study of adults seen in the emergency department or hospitalized with ischemic stroke or transient ischemic attack between July 1, 2003, and April 1, 2013, and included in the provincial stroke registry. We ascertained immigration status using immigration records and compared processes of stroke care delivery between immigrants (defined as those immigrating after 1985) and long-term residents. In the subgroup with ischemic stroke, we calculated inverse probability treatment weight (IPTW)-adjusted risk ratios for disability on discharge (modified Rankin Scale score of 3 to 5), accounting for demographic characteristics and comorbid conditions to compare outcomes between immigrants and long-term residents. Results- We included 34 987 patients with ischemic stroke or transient ischemic attack, of whom 2649 (7.6%) were immigrants. Immigrants were younger than long-term residents at the time of stroke/transient ischemic attack (median age 67 years versus 76 years; P<0.001). In the subgroup with ischemic stroke, there were no differences in stroke care delivery, except that a higher proportion of immigrants received thrombolysis than long-term residents (21.2% versus 15.5%; P<0.001). Immigrants with ischemic stroke had a higher adjusted risk of being disabled on discharge (adjusted risk ratio, 1.18; 95% CI, 1.13-1.22) compared to long-term residents. Conclusions- Stroke care is similar in Canadian immigrants and long-term residents. Future research is needed to confirm the observed association between immigration status and disability after stroke and to identify factors underlying the association.

Keywords: acculturation; immigration; patient outcome assessment; stroke; transient ischemic attack.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Anticoagulants / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Carotid Arteries / diagnostic imaging
  • Cohort Studies
  • Comorbidity
  • Coronary Artery Disease / epidemiology
  • Deglutition Disorders / diagnosis
  • Diabetes Mellitus / epidemiology
  • Echocardiography / statistics & numerical data
  • Electrocardiography, Ambulatory / statistics & numerical data
  • Emigrants and Immigrants / statistics & numerical data*
  • Emigration and Immigration
  • Female
  • Healthcare Disparities / statistics & numerical data
  • Hospital Mortality
  • Humans
  • Hypertension / epidemiology
  • Hypolipidemic Agents / therapeutic use
  • Ischemic Attack, Transient / therapy*
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Ontario / epidemiology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Retrospective Studies
  • Severity of Illness Index
  • Smoking / epidemiology
  • Stroke / therapy*
  • Thrombolytic Therapy / statistics & numerical data*
  • Time-to-Treatment / statistics & numerical data*

Substances

  • Anticoagulants
  • Antihypertensive Agents
  • Hypolipidemic Agents
  • Platelet Aggregation Inhibitors