Two-dimensional antibacterial Pd@Ag nanosheets with a synergetic effect of plasmonic heating and Ag+ release

Shiguang Mo; Xiaolan Chen; Mei Chen; Caiyun He; Yinghua Lu; Nanfeng Zheng

doi:10.1039/c5tb00830a

Two-dimensional antibacterial Pd@Ag nanosheets with a synergetic effect of plasmonic heating and Ag⁺ release

J Mater Chem B. 2015 Aug 14;3(30):6255-6260. doi: 10.1039/c5tb00830a. Epub 2015 Jul 6.

Authors

Shiguang Mo¹, Xiaolan Chen, Mei Chen, Caiyun He, Yinghua Lu, Nanfeng Zheng

Affiliation

¹ State Key Laboratory for Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Engineering Research Center for Nano-Preparation Technology of Fujian Province, and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China. chenxl@xmu.edu.cn nfzheng@xmu.edu.cn.

PMID: 32262744
DOI: 10.1039/c5tb00830a

Abstract

In this work, a novel bactericidal agent based on two-dimensional Pd@Ag nanosheets (Pd@Ag NSs) that is responsive to near-infrared (NIR) light has been developed. These Pd@Ag NSs were prepared by reducing silver ions on the surface of Pd nanosheets (Pd NSs) seeds by formaldehyde, and displayed excellent NIR absorption and photothermal conversion properties. In addition, the NIR irradiation triggers the release of more Ag⁺ from the Pd@Ag NSs. Upon exposure to a NIR laser at a low power density (0.5 W cm^-2), Pd@Ag NSs kill both Gram-negative (Escherichia coli, E. coli) and Gram-positive (Staphylococcus aureus, S. aureus) bacteria effectively by the synergistic effect of plasmonic heating and Ag⁺ release, which is much higher than either plasmonic heating or Ag⁺ alone. Such a novel nanomaterial is promising as an adjuvant therapeutic method for the treatment of patients suffering from severe bacterial infections.