From the wax cast of brain ventricles (1508-9) by Leonardo da Vinci to air cast ventriculography (1918) by Walter E. Dandy

Rev Neurol (Paris). 2020 May;176(5):393-396. doi: 10.1016/j.neurol.2019.11.005. Epub 2020 Mar 10.

Abstract

The mold of the human cerebral ventricles produced in 1918 by Walter E. Dandy had an experimental precedent, a wax cast of ox ventricles made four hundred years earlier (1508-9) by Leonardo da Vinci (1452-1519). This paper is an homage to the epitome of Renaissance and polymath Leonard da Vinci, as well as to Walter Edward Dandy (1886-1946) who developed the ventriculography (1918) and pneumoencephalography (1919) techniques. Pneumoencephalography was applied broadly up to the late 1970s, when it was replaced by less invasive and more accurate neuroimaging techniques.

Keywords: Cerebrospinal fluid; Leonardo da Vinci; Pneumoencephalography; Ventricles; Ventriculography; Walter Edward Dandy.

Publication types

  • Biography
  • Historical Article

MeSH terms

  • Casts, Surgical* / history
  • Cerebral Ventricles / anatomy & histology*
  • Cerebral Ventricles / diagnostic imaging*
  • Famous Persons
  • History, 16th Century
  • History, 20th Century
  • Humans
  • Medicine in the Arts / history
  • Neuroimaging / history*
  • Waxes / chemistry*
  • Waxes / history

Substances

  • Waxes

Personal name as subject

  • Walter E Dandy
  • Leonardo da Vinci