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J Laryngol Otol. 1988 Nov;102(11):1064-7.

Tumefactive fibroinflammatory lesion of the head and neck.

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  • 1Dept. of Otolaryngology & Pathology, Medical Faculty, University Kebangsaan Malaysia, Kuala Lumpur.


The term tumefactive fibroinflammatory lesion is used to describe an unusual fibrosclerosing disorder that behaves in a malignant way clinically but is histologically benign. Lesions in the head and neck are believed to be part of the broader fibrosclerosing syndrome which include pseudotumour of the orbit, Reidel's thyroiditis, sclerosing cholangitis and mediastinal fibrosis. Clinical diagnosis is often difficult and relies heavily on histopathology. Steroid therapy is suggested as the first line of management, while surgery or radiation therapy is reserved for failures.

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