New predictors for immunotherapy responses sharpen our view of the tumour microenvironment

Nature. 2020 Jan;577(7791):474-476. doi: 10.1038/d41586-019-03943-0.

Abstract

Three studies reveal that the presence in tumours of two key immune components — B cells and tertiary lymphoid structures — is associated with favourable outcomes when individuals undergo immunotherapy.

Keywords: Cancer; Immunology; Medical research.

Publication types

  • News
  • Comment

MeSH terms

  • Humans
  • Immunologic Factors
  • Immunotherapy
  • Melanoma*
  • Neoplasms*
  • Tertiary Lymphoid Structures*
  • Tumor Microenvironment

Substances

  • Immunologic Factors