Management of dyslipidemia in pediatric renal transplant recipients

Pediatr Nephrol. 2021 Jan;36(1):51-63. doi: 10.1007/s00467-019-04428-y. Epub 2020 Jan 2.

Abstract

Dyslipidemia after kidney transplantation is a common complication that has historically been underappreciated, especially in pediatric recipients. It is also a major modifiable risk factor for cardiovascular disease, a top cause of morbidity and mortality of transplant patients. While most knowledge about post-transplant dyslipidemia has been generated in adults, recommendations and treatment strategies also exist for children and are presented in this review. Awareness of these applicable guidelines and approaches is required, but not sufficient, for the reliable management of dyslipidemia in our patients, and additional needs and opportunities for comprehensive care in this area (e.g., quality improvement) are outlined.

Keywords: Cholesterol; Dyslipidemia; Kidney; Pediatric; Transplant; Triglycerides.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / etiology
  • Cardiovascular Diseases* / prevention & control
  • Dyslipidemias* / diagnosis
  • Dyslipidemias* / drug therapy
  • Dyslipidemias* / etiology
  • Humans
  • Kidney Transplantation* / adverse effects
  • Risk Factors
  • Transplant Recipients