A facile one-pot green synthesis of β-cyclodextrin decorated porous graphene nanohybrid as a highly efficient adsorbent for extracting aflatoxins from maize and animal feeds

Najmeh Sheibani Tezerji; Mohammad Mehdi Foroughi; Rasoul Rezaei Bezenjani; Nezhat Jandaghi; Ebrahim Rezaeipour; Forogh Rezvani

doi:10.1016/j.foodchem.2019.125747

A facile one-pot green synthesis of β-cyclodextrin decorated porous graphene nanohybrid as a highly efficient adsorbent for extracting aflatoxins from maize and animal feeds

Food Chem. 2020 May 1:311:125747. doi: 10.1016/j.foodchem.2019.125747. Epub 2019 Oct 21.

Authors

Najmeh Sheibani Tezerji¹, Mohammad Mehdi Foroughi², Rasoul Rezaei Bezenjani³, Nezhat Jandaghi², Ebrahim Rezaeipour⁴, Forogh Rezvani⁵

Affiliations

¹ Department of Chemistry, Faculty of Sciences, Islamic Azad University, Kerman Branch, Kerman, Iran; Iranian National Standards Organization of Hormozgan, Iran.
² Department of Chemistry, Faculty of Sciences, Islamic Azad University, Kerman Branch, Kerman, Iran.
³ Department of Chemistry, Faculty of Sciences, Islamic Azad University, Kerman Branch, Kerman, Iran; National Iranian Copper Industries Company, Iran.
⁴ Department of Chemistry, Faculty of Sciences, Shahid Bahonar University, Kerman, Iran; Iranian National Standards Organization of Hormozgan, Iran. Electronic address: e_rezaeipour@yahoo.com.
⁵ Iranian National Standards Organization of Hormozgan, Iran.

PMID: 31864190
DOI: 10.1016/j.foodchem.2019.125747

Abstract

In this paper, β-cyclodextrin (β-CD) supported on porous graphene nanohybrid (β-CDPG) was obtained by self-assembly of functionalized graphene nanosheets into a three-dimensional network in the presence of ascorbic acid via an in situ graphene oxide reduction and β-CD functionalization process during a hydrothermal reaction. The prepared supramolecular nanohybrid was further packed into a reusable syringe filter holder and applied as an adsorbent for solid phase extraction of four aflatoxins (B1, B2, G1, G2). Under optimal conditions, the detection limits and linear dynamic ranges were achieved in the range of 0.0075-0.030 μg kg^-1 and 0.025-100 μg kg^-1, respectively and the relative standard deviations were less than 6.1%. Good recoveries were observed for analyzing target AFs in maize and cereal-based chicken feed samples ranged from 90.5 to 105%. The method offered simultaneous advantages of high supramolecular recognition and enrichment capability of β-CD and the high specific surface area of the porous graphene.

Keywords: Aflatoxin; Aflatoxin B1 (PubChem CID 186907); Aflatoxin B2 (PubChem CID 2724360); Aflatoxin G1 (PubChem CID 14421); Aflatoxin G2 (PubChem CID 2724362); Food/feed; High-performance liquid chromatography; Porous graphene; Solid phase extraction; β-Cyclodextrin.

MeSH terms

Aflatoxins / isolation & purification*
Animal Feed / analysis*
Animals
Chromatography, High Pressure Liquid / methods
Graphite / chemistry*
Green Chemistry Technology / methods*
Limit of Detection
Porosity
Solid Phase Extraction / methods
Zea mays / chemistry*
beta-Cyclodextrins / chemistry*

Substances

Aflatoxins
beta-Cyclodextrins
Graphite