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J Reprod Med. 1988 Jul;33(7):630-2.

Suppression of lactation. A comparison of bromocriptine and prostaglandin E2.

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  • 1Department of Obstetrics and Gynaecology, Johannesburg Hospital, South Africa.


Women in the puerperium who requested lactation suppression were randomly allocated to receive bromocriptine from puerperal day 1 to 14 or prostaglandin E2 from day 3 or 4 for 24 hours. Subjectively, lactation suppression was satisfactory in all cases. Objective measurements showed a trend toward more-effective early suppression with bromocriptine. After discharge from the hospital, 3 of the 21 women who received prostaglandin E2 complained of mild breast tenderness, whereas 10 of the 22 who received bromocriptine reported severe "rebound" breast tenderness.

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