Levetiracetam is a useful alternative to phenytoin for epileptic seizures in children

BMJ. 2019 Nov 11:367:l5464. doi: 10.1136/bmj.l5464.

Abstract

The studyLyttle MD, Rainford NEA, Gamble C, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet 2019;393:2125-34.This trial was funded by the NIHR Health Technology Assessment Programme (project number 12/127/134).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000790/levetiracetam-vs-phenytoin-in-stopping-childrens-prolonged-epileptic-seizures.

Publication types

  • Comment

MeSH terms

  • Child
  • Epilepsy*
  • Humans
  • Levetiracetam
  • Phenytoin
  • Seizures
  • Status Epilepticus*

Substances

  • Levetiracetam
  • Phenytoin