Trichosporon japonicum Fungemia and Ventricular Assist Device Infection in an Immunocompetent Patient

Felix Bongomin; Akaninyene Otu; Giorgio Calisti; Malcolm D Richardson; James Barnard; Rajamiyer Venkateswaran; Paschalis Vergidis

doi:10.1093/ofid/ofz343

Trichosporon japonicum Fungemia and Ventricular Assist Device Infection in an Immunocompetent Patient

Open Forum Infect Dis. 2019 Jul 23;6(9):ofz343. doi: 10.1093/ofid/ofz343. eCollection 2019 Sep.

Authors

Felix Bongomin¹, Akaninyene Otu², Giorgio Calisti³, Malcolm D Richardson⁴, James Barnard⁵, Rajamiyer Venkateswaran^{5

6}, Paschalis Vergidis⁷

Affiliations

¹ Department of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.
² Department of Infectious Diseases, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK; The University of Manchester, Manchester, UK.
³ Department of Microbiology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
⁴ Mycology Reference Centre Manchester, ECMM Centre of Excellence in Clinical and Laboratory Mycology and Clinical Studies, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
⁵ Department of Cardiothoracic Surgery, Wythenshawe Hospital Manchester University NHS Foundation Trust, Manchester, UK.
⁶ Division of Cardiovascular Sciences, The University of Manchester, Manchester, UK.
⁷ Mayo Clinic, Rochester, Minnesota.

Abstract

Trichosporon species are emerging opportunistic yeasts that cause life-threatening disseminated disease in severely immunocompromised patients. Trichosporon japonicum is a very rare cause of invasive trichosporonosis. We describe a case of Trichosporon japonicum fungemia in an immunocompetent patient with a transcutaneous biventricular assist device.

Keywords: MALDI TOF; Trichosporon japonicum; antifungal therapy; ventricular assist device.

Publication types

Case Reports