DJ-1 is dispensable for human stem cell homeostasis

Fang Cheng; Si Wang; Moshi Song; Zunpeng Liu; Ping Liu; Lei Wang; Yanjiang Wang; Qian Zhao; Kaowen Yan; Piu Chan; Weiqi Zhang; Jing Qu; Guang-Hui Liu

doi:10.1007/s13238-019-00659-9

DJ-1 is dispensable for human stem cell homeostasis

Protein Cell. 2019 Nov;10(11):846-853. doi: 10.1007/s13238-019-00659-9.

Authors

Fang Cheng^{1

2}, Si Wang^{3

4

2}, Moshi Song^{3

2

5}, Zunpeng Liu^{6

2}, Ping Liu^{1

2}, Lei Wang^{1

2}, Yanjiang Wang⁷, Qian Zhao⁴, Kaowen Yan³, Piu Chan⁴, Weiqi Zhang^{8

9

10

11}, Jing Qu^{12

13

14}, Guang-Hui Liu^{15

16

17

18

19}

Affiliations

¹ National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
² University of Chinese Academy of Sciences, Beijing, 100049, China.
³ State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
⁴ Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
⁵ Institute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China.
⁶ State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
⁷ Department of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
⁸ Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, 100053, China. zhangwq@big.ac.cn.
⁹ CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China. zhangwq@big.ac.cn.
¹⁰ University of Chinese Academy of Sciences, Beijing, 100049, China. zhangwq@big.ac.cn.
¹¹ Institute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China. zhangwq@big.ac.cn.
¹² State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. qujing@ioz.ac.cn.
¹³ University of Chinese Academy of Sciences, Beijing, 100049, China. qujing@ioz.ac.cn.
¹⁴ Institute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China. qujing@ioz.ac.cn.
¹⁵ National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. ghliu@ibp.ac.cn.
¹⁶ Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, 100053, China. ghliu@ibp.ac.cn.
¹⁷ University of Chinese Academy of Sciences, Beijing, 100049, China. ghliu@ibp.ac.cn.
¹⁸ Institute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China. ghliu@ibp.ac.cn.
¹⁹ Translational Medical Center for Stem Cell Therapy, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. ghliu@ibp.ac.cn.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

DNA-Binding Proteins / metabolism*
Endothelial Cells / cytology*
Human Embryonic Stem Cells / cytology*
Humans
Mesenchymal Stem Cells / cytology*
Mitochondria / metabolism
Mitochondrial Proteins / metabolism
Neural Stem Cells / cytology*
Protein Deglycase DJ-1 / physiology*
Transcription Factors / metabolism*

Substances

CHCHD2 protein, human
DNA-Binding Proteins
Mitochondrial Proteins
Transcription Factors
PARK7 protein, human
Protein Deglycase DJ-1