Somat Cell Mol Genet. 1988 Mar;14(2):217-21.

Structural gene encoding human factor XII is located at 5q33-qter.

Royle NJ, Nigli M, Cool D, MacGillivray RT, Hamerton JL.

Source

Department of Human Genetics, University of Manitoba, Canada.

Abstract

The gene encoding human factor XII (F12) or Hageman factor has been mapped to 5q33-qter. This has been achieved by analyzing the results obtained from hybridizing a cloned fragment from the factor XII gene to a panel of human-hamster somatic cell hybrid DNAs and also by in situ hybridization to normal human metaphase cells. The previously reported results localizing F12 to 6p23 are discussed.

PMID:: 3162339; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

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Factor XII

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Cited by 2 PubMed Central articles

Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels. [Hum Mol Genet. 2010]
Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels.
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A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. [Am J Hum Genet. 2002]
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease.
Soria JM, Almasy L, Souto JC, Bacq D, Buil A, Faure A, Martínez-Marchán E, Mateo J, Borrell M, Stone W, et al. Am J Hum Genet. 2002 Mar; 70(3):567-74. Epub 2002 Jan 22.

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Structural gene encoding human factor XII is located at 5q33-qter.
Structural gene encoding human factor XII is located at 5q33-qter.
Somat Cell Mol Genet. 1988 Mar ;14(2):217-21.

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