Science. 1985 Jun 7;228(4704):1201-4.

Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.

Daniel MD, Letvin NL, King NW, Kannagi M, Sehgal PK, Hunt RD, Kanki PJ, Essex M, Desrosiers RC.

Abstract

The isolation of a T-cell tropic retrovirus from three immunodeficient macaques and one macaque with lymphoma is described. The morphology, growth characteristics, and antigenic properties of this virus indicate that it is related to the causative agent of acquired immune deficiency syndrome in humans (HTLV-III or LAV). This virus is referred to as simian T-lymphotropic virus type III (STLV-III) of macaques. The existence of a cytopathic, T-cell tropic virus resembling HTLV-III in monkeys may facilitate study of disease induction and vaccine development in an animal model.

PMID:: 3159089; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Supplemental Content

Save items

Related citations in PubMed

Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. [Science. 1985]
Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III.
Kanki PJ, McLane MF, King NW Jr, Letvin NL, Hunt RD, Sehgal P, Daniel MD, Desrosiers RC, Essex M. Science. 1985 Jun 7; 228(4704):1199-201.
Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome. [J Clin Invest. 1986]
Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome.
Kannagi M, Kiyotaki M, Desrosiers RC, Reimann KA, King NW, Waldron LM, Letvin NL. J Clin Invest. 1986 Nov; 78(5):1229-36.
Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. [Science. 1985]
Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III.
Letvin NL, Daniel MD, Sehgal PK, Desrosiers RC, Hunt RD, Waldron LM, MacKey JJ, Schmidt DK, Chalifoux LV, King NW. Science. 1985 Oct 4; 230(4721):71-3.
Review Retroviruses associated with leukemia and ablative syndromes in animals and in human beings. [Cancer Res. 1985]
Review Retroviruses associated with leukemia and ablative syndromes in animals and in human beings.
Essex M, McLane MF, Kanki P, Allan J, Kitchen L, Lee TH. Cancer Res. 1985 Sep; 45(9 Suppl):4534s-4538s.
Review The origins of HIV-1 and HTLV-4/HIV-2. [Ann N Y Acad Sci. 1987]
Review The origins of HIV-1 and HTLV-4/HIV-2.
Kanki PJ, Hopper JR, Essex M. Ann N Y Acad Sci. 1987; 511:370-5.

See reviews... See all...

Cited by over 100 PubMed Central articles

Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity. [PLoS Pathog. 2013]
Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity.
McCarthy KR, Schmidt AG, Kirmaier A, Wyand AL, Newman RM, Johnson WE. PLoS Pathog. 2013 May; 9(5):e1003352. Epub 2013 May 9.
Virus-associated lymphomagenesis. [Int J Biomed Sci. 2006]
Virus-associated lymphomagenesis.
Tarantul VZ. Int J Biomed Sci. 2006 Jun; 2(2):101-13.
No monkey business: why studying NK cells in non-human primates pays off. [Front Immunol. 2013]
No monkey business: why studying NK cells in non-human primates pays off.
Hong HS, Rajakumar PA, Billingsley JM, Reeves RK, Johnson RP. Front Immunol. 2013; 4:32. Epub 2013 Feb 18.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
Science. 1985 Jun 7 ;228(4704):1201-4.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: