Consumption of Korean Foods with High Flavonoid Contents Reduces the Likelihood of Having Elevated C-Reactive Protein Levels: Data from the 2015-2017 Korea National Health and Nutrition Examination Survey

Nutrients. 2019 Oct 4;11(10):2370. doi: 10.3390/nu11102370.

Abstract

This study was conducted to investigate associations between C-reactive protein (CRP) levels and Korean food (KF) consumption and flavonoid intake from the 2015-2017 Korea National Health and Nutrition Examination Survey. A total of 6025 men and 8184 women (≥19 years) who completed a 24-h dietary recall and health examination were analyzed. The individual KF consumption rate was defined as the proportion of KF of total food consumed and categorized into tertiles. Odds ratios (ORs) for elevated CRP levels (>3.0 mg/L) according to KF consumption rate and flavonoid intake/dietary total antioxidant capacity (TAC) (<median; ≥median) were obtained by multiple logistic regression. KF consumption was inversely associated with CRP levels in women (p = 0.0236) and positively associated with flavonoid intake/dietary TAC in both sexes (p < 0.0001). Compared to women who consumed less than the median amount of flavonoid or TAC with KF consumption rates in the lowest tertile, those who consumed more flavonoid (OR = 0.59, 95% CI 0.42-0.83) or TAC (OR = 0.58, 95% CI 0.41-0.82) in the highest tertile showed significantly lower ORs for elevated CRP levels. Thus, consuming KFs rich in flavonoid is effective for regulating CRP levels.

Keywords: C-reactive protein; Korea National Health and Nutrition Examination Survey; Korean food; flavonoids; total antioxidant capacity.

MeSH terms

  • Adult
  • Aged
  • Anti-Inflammatory Agents / administration & dosage*
  • Antioxidants / administration & dosage*
  • Biomarkers / blood
  • C-Reactive Protein / analysis*
  • Cross-Sectional Studies
  • Diet, Healthy*
  • Down-Regulation
  • Female
  • Flavonoids / administration & dosage*
  • Humans
  • Inflammation / blood
  • Inflammation / diagnosis
  • Inflammation / prevention & control*
  • Male
  • Middle Aged
  • Nutrition Surveys
  • Protective Factors
  • Republic of Korea
  • Risk Assessment
  • Risk Factors
  • Risk Reduction Behavior*
  • Sex Factors
  • Time Factors
  • Young Adult

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Biomarkers
  • Flavonoids
  • C-Reactive Protein