Prevalence of Obsessive-Compulsive Symptoms in Elderly Parkinson Disease Patients: A Case-Control Study

Am J Geriatr Psychiatry. 2020 Feb;28(2):167-175. doi: 10.1016/j.jagp.2019.08.022. Epub 2019 Aug 29.

Abstract

Background: The clinical picture of obsessive-compulsive disorder encompasses a broad range of symptoms that are related to multiple psychological domains, including perception, cognition, emotion, and social relatedness. As obsessive-compulsive symptoms (OCS) frequently have an early onset, there are limited data about OCS in older populations (≥65 years) and, in particular, in elderly subjects with Parkinson disease (PD).

Objective: This study aimed to estimate the prevalence of OCS using a self-report measure (Obsessive-Compulsive Inventory-Revised) and to identify associated sociodemographic and clinical factors in a sample of elderly PD patients compared to a comparison group of similarly aged healthy volunteers.

Results: The mean age was 74 ± 6 years in the PD patients and 73 ± 7 years in the comparison group. The mean disease duration was 9.6 ± 5.8 years. Among the PD patients, 30.7% reported at least one OCS or a related disorder compared to 21.1% in the comparison group. Hoarding was significantly more common in PD patients than in the comparison group.

Conclusions: Subclinical OCS were present at a high percentage in both PD patients and comparison group. The OCS phenotype in PD may present differently, as hoarding was more common in PD patients.

Keywords: Obsessive-compulsive disorder; Parkinson disease; elderly; hoarding.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Comorbidity
  • Compulsive Behavior / epidemiology*
  • Female
  • Humans
  • Linear Models
  • Male
  • Obsessive Behavior / epidemiology*
  • Parkinson Disease / epidemiology*
  • Prevalence
  • Risk
  • Self Report