We present a comprehensive study on anisotropic magnetocaloric porperties of the van der Waals weak-itinerant ferromagnet Fe3-xGeTe2 that features gate-tunable room-temperature ferromagnetism in few-layer device. Intrinsic magnetocrystalline anisotropy is observed to be temperature-dependent and most likely favors the long-range magnetic order in thin Fe3-xGeTe2 crsytal. The magnetic entropy change ΔSM also reveals an anisotropic characteristic between H//ab and H//c, which could be well scaled into a universal curve. The peak value [Formula: see text] of 1.20 J kg-1 K-1 and the corresponding adiabatic temperature change ΔTad of 0.66 K are deduced from heat capacity with out-of-plane field change of 5 T. By fitting of the field-dependent parameters of [Formula: see text] and the relative cooling power RCP, it gives [Formula: see text] ∝ Hn with n = 0.603(6) and RCP ∝ Hm with m = 1.20(1) when H//c. Given the high and tunable Tc, Fe3-xGeTe2 crystals are of interest for fabricating the heterostructure-based spintronics device.