Biological, nutritional, and therapeutic significance of Moringa oleifera Lam

Phytother Res. 2019 Nov;33(11):2870-2903. doi: 10.1002/ptr.6475. Epub 2019 Aug 27.

Abstract

The genus Moringa Adans. comprises 13 species, of which Moringa oleifera Lam. native to India and cultivated across the world owing to its drought and frost resistance habit is widely used in traditional phytomedicine and as rich source of essential nutrients. Wide spectrum of phytochemical ingredients among leaf, flower, fruit, seed, seed oil, bark, and root depend on cultivar, season, and locality. The scientific studies provide insights on the use of M. oleifera with different aqueous, hydroalcoholic, alcoholic, and other organic solvent preparations of different parts for therapeutic activities, that is, antibiocidal, antitumor, antioxidant, anti-inflammatory, cardio-protective, hepato-protective, neuro-protective, tissue-protective, and other biological activities with a high degree of safety. A wide variety of alkaloid and sterol, polyphenols and phenolic acids, fatty acids, flavanoids and flavanol glycosides, glucosinolate and isothiocyanate, terpene, anthocyanins etc. are believed to be responsible for the pragmatic effects. Seeds are used with a view of low-cost biosorbent and coagulant agent for the removal of metals and microbial contamination from waste water. Thus, the present review explores the use of M. oleifera across disciplines for its prominent bioactive ingredients, nutraceutical, therapeutic uses and deals with agricultural, veterinarian, biosorbent, coagulation, biodiesel, and other industrial properties of this "Miracle Tree."

Keywords: Moringa oleifera; nutritional properties; phytochemistry; therapeutic activities; water purification.

Publication types

  • Review

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Dietary Supplements
  • Flowers / chemistry
  • Fruit / chemistry
  • Humans
  • India
  • Moringa oleifera / chemistry*
  • Nutritional Physiological Phenomena / drug effects
  • Nutritive Value*
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology
  • Phytochemicals / therapeutic use
  • Phytotherapy* / methods
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use*
  • Plant Leaves / chemistry
  • Seeds / chemistry

Substances

  • Antioxidants
  • Phytochemicals
  • Plant Extracts