Rhodium(iii)-catalyzed unreactive C(sp3)-H alkenylation of N-alkyl-1H-pyrazoles with alkynes

Org Biomol Chem. 2019 Sep 7;17(33):7679-7683. doi: 10.1039/c9ob01531k. Epub 2019 Aug 6.

Abstract

The first example of pyrazole-directed rhodium(iii)-catalyzed unreactive C(sp3)-H alkenylation with alkynes has been described, which showed a relatively broad substrate scope with good functional group compatibility. Moreover, we demonstrated that the transitive coordinating center pyrazole could be easily removed under mild conditions.

Publication types

  • Research Support, Non-U.S. Gov't