Severe purulent pericarditis caused by invasive Eikenella corrodens: case report and literature review

BMC Infect Dis. 2019 Jul 23;19(1):657. doi: 10.1186/s12879-019-4256-0.

Abstract

Background: Eikenella corrodens is a slowly growing gram-negative bacillus that can cause severe invasive disease in human. Although E. corrodens infections in various sites of human body have been well described, pericarditis caused by invasive E. corrodens has rarely been reported.

Case presentation: Here we report the case of a 63-year old male with a complaint of left shoulder pain. The patient was diagnosed as purulent pericarditis by chest computed tomography scan and ultrasound-guided pericardiocentesis, and the pathogen of E. corrodens was identified in the pericardial fluid culture. The clinical condition of the patient deteriorated quickly, and he died right after the drainage surgery even though the pathogen was sensitive to antibiotics treatment.

Conclusion: E. corrodens is a rare pericarditis associated pathogen. Purulent pericarditis caused by E. corrodens presents atypical manifestations and rapid progression of infection in immunosuppressed individuals such as neutropenic patients. Earlier diagnosis and proper drainage surgery with effective antibiotics treatment may improve the prognosis.

Keywords: Eikenella corrodens; Infection; Pericarditis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Eikenella corrodens / drug effects
  • Eikenella corrodens / pathogenicity*
  • Female
  • Gram-Negative Bacterial Infections / diagnostic imaging
  • Gram-Negative Bacterial Infections / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Pericardiocentesis
  • Pericarditis / diagnostic imaging
  • Pericarditis / drug therapy*
  • Pericarditis / surgery
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents