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1: Br J Dermatol. 1988 Mar;118(3):425-7.Links

Comparison of a hydrocolloid dressing and paraffin gauze in the treatment of venous ulcers.

Handfield-Jones SE, Grattan CE, Simpson RA, Kennedy CT.

Department of Dermatology, Bristol Royal Infirmary, U.K.

In-patients with venous leg ulcers showed increased healing rates with a hydrocolloid dressing (Granuflex), as compared with a traditional paraffin gauze dressing (Jelonet), in a randomized sequential crossover trial, although the difference was not statistically significant. Bacteriological studies showed that the hydrocolloid dressing favoured growth of both aerobes and anaerobes in significantly greater numbers compared with paraffin gauze. Heavy bacterial colonization had no effect on the healing rates of the ulcers. Granuflex is said to produce an anaerobic environment--survival of Pseudomonas aeruginosa, a strict aerobe, under Granuflex dressings, makes this seem unlikely.

PMID: 3128320 [PubMed - indexed for MEDLINE]