Destructive Upper Airway Disease from Eosinophilic Granulomatosis with Polyangiitis (EGPA): The Very First Case

Biplab Saha; Aditi Saha; Fernanda Cordeiro-Rudnisky; Boris Shkolnik; Scott Beegle

doi:10.1155/2019/6173869

Destructive Upper Airway Disease from Eosinophilic Granulomatosis with Polyangiitis (EGPA): The Very First Case

Case Rep Rheumatol. 2019 May 23:2019:6173869. doi: 10.1155/2019/6173869. eCollection 2019.

Authors

Biplab Saha¹, Aditi Saha², Fernanda Cordeiro-Rudnisky³, Boris Shkolnik¹, Scott Beegle¹

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY, USA.
² Department of Medicine, Saint Barnabas Medical Center, Livingston, NJ, USA.
³ Department of Pathology, Albany Medical Center, Albany, NY, USA.

Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystem vasculitic disorder that predominantly affects medium- and small-sized blood vessels. EGPA belongs to a group of vasculitides known as anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV). Upper airway involvement is seen in all ANCA-associated vasculitides, but destructive upper airway disease has never been reported in patients with EGPA. We report the first case of erosive chondritis and saddle nose deformity in a 50-year-old patient suffering from EGPA.

Publication types

Case Reports