Computed Tomography-guided Cryoablation for Adrenal Pheochromocytoma: Safety and Clinical Effectiveness

Surg Laparosc Endosc Percutan Tech. 2019 Oct;29(5):409-412. doi: 10.1097/SLE.0000000000000677.

Abstract

Purpose: To evaluate the safety and clinical effectiveness of computed tomography (CT)-guided cryoablation for adrenal pheochromocytoma (AP).

Materials and methods: From July 2015 to October 2018, we observed 8 patients that underwent CT-guided cryoablation for AP. The blood pressure and pulse before treatment did not exceed 150/90 mm Hg and 90 times/min, respectively. Complete ablation rate, clinical success rate, and long-term outcomes were analyzed.

Results: A total of 8 patients with 8 APs were treated by CT-guided cryoablation. The mean duration of the procedure was 67.5±4.6 minutes. No patient achieved complete ablation, yet the clinical success rate was 100%. The mean metanephrine decreased from 61.7±11.1 to 2.0±1.1 nmol/L (P<0.001). Hypertensive crisis was found in 5 (67.5%) patients during the procedure. During a mean follow-up of 16.9±13.4 months, no patient experienced tumor progression.

Conclusion: CT-guided cryoablation is an effective method for patients with AP.

MeSH terms

  • Adrenal Gland Neoplasms / diagnostic imaging
  • Adrenal Gland Neoplasms / surgery*
  • Adult
  • Cryosurgery / adverse effects
  • Cryosurgery / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Operative Time
  • Pheochromocytoma / diagnostic imaging
  • Pheochromocytoma / surgery*
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome