Nihon Geka Gakkai Zasshi. 1987 Apr;88(4):483-8.

[Selenium deficiency and cardiomyopathy in a patient on long-term parenteral nutrition].

[Article in Japanese]

Abstract

A 28 year-old Japanese male with Crohn's disease maintained on total parenteral nutrition for 5 consecutive years showed congestive cardiomyopathy. His symptoms (palpitation and precordial pain), arrhythmia on ECG and cardiomegaly on chest X-ray film were progressive. By intravenous selenium supplementation of 100 micrograms/day (selenite) his symptoms disappeared dramatically and plasma selenium level, erythrocyte selenium level and glutathione peroxidase activity improved to normal ranges. It is suggested that this myocardial damage was caused by selenium deficiency.

PMID:: 3108654; [PubMed - indexed for MEDLINE]

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SELENIUM, ELEMENTAL - HSDB

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Selenium deficiency and fatal cardiomyopathy in a patient receiving long-term home parenteral nutrition. [Clin Pharm. 1984]
Selenium deficiency and fatal cardiomyopathy in a patient receiving long-term home parenteral nutrition.
Quercia RA, Korn S, O'Neill D, Dougherty JE, Ludwig M, Schweizer R, Sigman R. Clin Pharm. 1984 Sep-Oct; 3(5):531-5.
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Cited by 1 PubMed Central article

Progressive encephalopathy in a Crohn's disease patient on long-term total parenteral nutrition: possible relationship to selenium deficiency. [Postgrad Med J. 1994]
Progressive encephalopathy in a Crohn's disease patient on long-term total parenteral nutrition: possible relationship to selenium deficiency.
Kawakubo K, Iida M, Matsumoto T, Mochizuki Y, Doi K, Aoyagi K, Fujishima M. Postgrad Med J. 1994 Mar; 70(821):215-9.

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