Format

Send to:

Choose Destination
See comment in PubMed Commons below
Am J Vet Res. 1986 Dec;47(12):2646-8.

Antibody-mediated suppression of erythropoiesis in dogs with red blood cell aplasia.

Abstract

Eight dogs with acquired RBC aplasia were studied. Unfractionated sera and serum immunoglobulin G fractions were examined for the presence of erythroid progenitor cell inhibitors. A serum immunoglobulin G inhibitor directed against precursors of erythroid colony-forming units was detected in 3 of 5 dogs that were direct Coombs' test-negative and in 1 of 3 dogs that were direct Coombs' test-positive. Sera from these dogs were treated with binary ethyleneimine to inactivate any viruses present. The inhibitory effects of the treated serum on erythroid colony-forming units was not ameliorated.

PMID:
3099614
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk