Globrauneine A-F: six new triterpenoid esters from the leaves of Globimetula braunii

Nat Prod Res. 2020 Oct;34(19):2746-2753. doi: 10.1080/14786419.2019.1586693. Epub 2019 Mar 31.

Abstract

Phytochemical study was conducted on the leaves of Globimetula braunii which is a hemi parasitic plant belonging to the family Loranthaceae. Extraction was carried out using cold extraction method with increasing polarity of solvents i.e n-hexane, CH2Cl2 and MeOH. The components were separated by chromatographic technique and the structures of the compounds were elucidated by extensive spectroscopic analyses including MS, FTIR, 1D and 2D NMR, HRMS and chemical methods. Six new pentacyclic triterpenoid esters named as globrauneine A (1), globrauneine B (2), globrauneine C (3), globrauneine D (4), globrauneine E (5), and globrauneine F (6), together with six known compounds (7 - 12) were successfully isolated from the leaves of G. braunii growing on Piliostigma thonningii. These results depict a substantial support to the chemotaxonomy of the genus Globimetula.

Keywords: Globimetula braunii; Loranthaceae; globrauneine A–F; triterpenoid esters.

MeSH terms

  • Esters / chemistry
  • Fabaceae / parasitology
  • Hexanes / chemistry
  • Loranthaceae / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry*
  • Solvents / chemistry
  • Spectroscopy, Fourier Transform Infrared
  • Triterpenes / chemistry*

Substances

  • Esters
  • Hexanes
  • Plant Extracts
  • Solvents
  • Triterpenes
  • n-hexane