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Arch Virol. 1986;90(1-2):173-81.

Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report.

Abstract

Nineteen influenza virus strains were examined for susceptibility to amantadine-HCl (AMT) and for pH-thresholds of haemagglutinin-induced haemolysis. Whereas pH-thresholds below 5.5 were not seen in AMT-resistant strains, AMT-sensitive strains showed pH-thresholds either below or above 5.5.

PMID:
3089198
[PubMed - indexed for MEDLINE]
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