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Arch Dermatol. 1978 Jul;114(7):1036-8.

Treatment of alopecia areata with dinitrochlorobenzene.

Abstract

Persistent refractory alopecia areata in 26 patients was treated topically with dinitrochlorobenzene (DNCB). Sixteen patients have had excellent regrowth of hair; three patients could either not be initially sensitized or an adequate allergic contact dermatitis on the scalp did not develop. Two patients discontinued therapy within two months; hair growth did not develop in five patients despite an adequate trial. Augmentation of the T-lymphocyte pool via DNCB sensitization and challenge may become effective therapy for some patients with severe alopecia areata.

PMID:
308348
[PubMed - indexed for MEDLINE]
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