Hepatocyte tPA: where have you been hiding?

Blood. 2019 Feb 14;133(7):631-632. doi: 10.1182/blood-2018-12-891515.

Abstract

In this issue of Blood, Zheng et al provide insight into the source of intravascular tissue–type plasminogen activator (tPA). They demonstrate an important role for hepatocytes in determining the basal level of plasma tPA and identify regulatory factors that control tPA expression by hepatocytes.

Publication types

  • Comment

MeSH terms

  • Fibrinolysis*
  • Hepatocytes*