Anal Biochem. 1988 Nov 15;175(1):5-13.

Firefly luciferase as a tool in molecular and cell biology.

Source

Department of Biology, University of California, San Diego, La Jolla 92093.

Abstract

The unique properties of firefly luciferase and the cloning of the gene for this enzyme have spawned a number of novel applications of this protein. We summarize a few of these applications including its use as a reporter gene, as a model for the study of protein import into peroxisomes, and as a component of a heterologous gene expression system.

PMID:: 3072883; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Related citations

The carboxyl-terminal tripeptide serine-lysine-leucine of firefly luciferase is necessary but not sufficient for peroxisomal import in yeast. [New Biol. 1992]
The carboxyl-terminal tripeptide serine-lysine-leucine of firefly luciferase is necessary but not sufficient for peroxisomal import in yeast.
Distel B, Gould SJ, Voorn-Brouwer T, van der Berg M, Tabak HF, Subramani S. New Biol. 1992 Feb; 4(2):157-65.
Import of firefly luciferase into peroxisomes of permeabilized Chinese hamster ovary cells: a model system to study peroxisomal protein import in vitro. [Exp Cell Res. 1993]
Import of firefly luciferase into peroxisomes of permeabilized Chinese hamster ovary cells: a model system to study peroxisomal protein import in vitro.
Rapp S, Soto U, Just WW. Exp Cell Res. 1993 Mar; 205(1):59-65.
Firefly luciferase is targeted to peroxisomes in mammalian cells. [Proc Natl Acad Sci U S A. 1987]
Firefly luciferase is targeted to peroxisomes in mammalian cells.
Keller GA, Gould S, Deluca M, Subramani S. Proc Natl Acad Sci U S A. 1987 May; 84(10):3264-8.
Review Introduction to beetle luciferases and their applications. [J Biolumin Chemilumin. 1989]
Review Introduction to beetle luciferases and their applications.
Wood KV, Lam YA, McElroy WD. J Biolumin Chemilumin. 1989 Jul; 4(1):289-301.
Review Biogenesis of peroxisomes in mammals. [Cell Biochem Funct. 1992]
Review Biogenesis of peroxisomes in mammals.
Just WW, Soto U. Cell Biochem Funct. 1992 Sep; 10(3):159-65.

See reviews... See all...

Cited by 18 PubMed Central articles

A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters. [PLoS One. 2012]
A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters.
Tchorz JS, Suply T, Ksiazek I, Giachino C, Cloëtta D, Danzer CP, Doll T, Isken A, Lemaistre M, Taylor V, et al. PLoS One. 2012; 7(1):e30011. Epub 2012 Jan 13.
A novel Gateway®-compatible binary vector allows direct selection of recombinant clones in Agrobacterium tumefaciens. [Plant Methods. 2011]
A novel Gateway®-compatible binary vector allows direct selection of recombinant clones in Agrobacterium tumefaciens.
Traore SM, Zhao B. Plant Methods. 2011 Dec 7; 7(1):42. Epub 2011 Dec 7.
Review Visceral leishmaniasis: experimental models for drug discovery. [Indian J Med Res. 2011]
Review Visceral leishmaniasis: experimental models for drug discovery.
Gupta S, Nishi. Indian J Med Res. 2011 Jan; 133:27-39.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Firefly luciferase as a tool in molecular and cell biology.
Firefly luciferase as a tool in molecular and cell biology.
Anal Biochem. 1988 Nov 15 ;175(1):5-13.

PubMed
A pilot trial of low-dose naltrexone in primary progressive multiple sclerosis.
A pilot trial of low-dose naltrexone in primary progressive multiple sclerosis.
Mult Scler. 2008 Sep ;14(8):1076-83.

PubMed
RNAMST: efficient and flexible approach for identifying RNA structural homologs.
RNAMST: efficient and flexible approach for identifying RNA structural homologs.
Nucleic Acids Res. 2006 Jul 1 ;34(Web Server issue):W423-8.

PubMed
Potential mechanisms of cancer chemoprevention by anthocyanins.
Potential mechanisms of cancer chemoprevention by anthocyanins.
Curr Mol Med. 2003 Mar ;3(2):149-59.

PubMed
Is it safe to preserve the nipple areola complex during skin-sparing mastectomy ...
Is it safe to preserve the nipple areola complex during skin-sparing mastectomy for breast cancer?
Int J Fertil Womens Med. 2006 Sep-Oct ;51(5):230-2.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: