Age-Related Changes in Gut Microbiota Alter Phenotype of Muscularis Macrophages and Disrupt Gastrointestinal Motility

Cell Mol Gastroenterol Hepatol. 2019;7(1):243-245.e2. doi: 10.1016/j.jcmgh.2018.09.001. Epub 2018 Sep 17.

Authors

Laren Becker¹, Estelle T Spear², Sidhartha R Sinha², Yeneneh Haileselassie², Aida Habtezion³

Affiliations

¹ Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University, Stanford, California. Electronic address: lsbecker@stanford.edu.
² Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University, Stanford, California.
³ Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University, Stanford, California. Electronic address: aidah@stanford.edu.

No abstract available

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Aging / pathology*
Animals
Gastrointestinal Microbiome*
Gastrointestinal Motility*
Intestinal Mucosa / pathology*
Macrophages / pathology*
Mice, Knockout
Phenotype
Receptors, G-Protein-Coupled / deficiency
Receptors, G-Protein-Coupled / metabolism

Substances

Gpbar1 protein, mouse
Receptors, G-Protein-Coupled

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