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J Med Primatol. 1988;17(2):105-12.

Use of ultrasound for early pregnancy detection in the rhesus and cynomolgus macaque (Macaca mulatta and Macaca fascicularis).

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  • 1Developmental and Reproductive Biology Unit, University of California, Davis.


Diagnostic ultrasound provides an accurate method for the detection of early pregnancy and embryonic loss in macaque species. A developing gestational sac (GS) may be observed on gestational day (GD) 14-15 with positive identification on GD 16-18. Visualization of the yolk sac, embryo, and developing heart on GD 21-25 confirms pregnancy. Continuous observations during embryogenesis provide useful information when assessing the teratogenic potential of a variety of agents.

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