MAGpy: a reproducible pipeline for the downstream analysis of metagenome-assembled genomes (MAGs)

Bioinformatics. 2019 Jun 1;35(12):2150-2152. doi: 10.1093/bioinformatics/bty905.

Abstract

Motivation: Metagenomics is a powerful tool for assaying the DNA from every genome present in an environment. Recent advances in bioinformatics have enabled the rapid assembly of near-complete metagenome-assembled genomes (MAGs), and there is a need for reproducible pipelines that can annotate and characterize thousands of genomes simultaneously, to enable identification and functional characterization.

Results: Here we present MAGpy, a scalable and reproducible pipeline that takes multiple genome assemblies as FASTA and compares them to several public databases, checks quality, suggests a taxonomy and draws a phylogenetic tree.

Availability and implementation: MAGpy is available on github: https://github.com/WatsonLab/MAGpy.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Metagenome*
  • Metagenomics
  • Phylogeny
  • Software*