Abstract
The unique photophysical properties of Ru(ii) polypyridyl complexes make them very attractive candidates as photosensitisers in Photodynamic Therapy (PDT). However, to date, there are not many studies exploring in detail the mechanism(s) of action of such compounds in living systems upon light irradiation. This feature article provides an overview of the most in-depth biological studies on such compounds.
MeSH terms
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Animals
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Cell Line, Tumor
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Cell Proliferation / drug effects
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Coordination Complexes / chemistry
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Coordination Complexes / pharmacology*
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Humans
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Light*
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Neoplasms / drug therapy*
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Neoplasms / pathology
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Photochemotherapy*
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Photosensitizing Agents / chemistry
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Photosensitizing Agents / pharmacology*
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Polymers / chemistry
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Polymers / pharmacology
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Pyridines / chemistry
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Pyridines / pharmacology
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Ruthenium / chemistry
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Ruthenium / pharmacology
Substances
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Antineoplastic Agents
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Coordination Complexes
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Photosensitizing Agents
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Polymers
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Pyridines
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Ruthenium