Acrodermatitis chronica atrophicans in children: Report on two cases and review of the literature

Ticks Tick Borne Dis. 2019 Jan;10(1):180-185. doi: 10.1016/j.ttbdis.2018.10.009. Epub 2018 Oct 26.

Abstract

Acrodermatitis chronica atrophicans is a late manifestation of European Lyme borreliosis and is characterized by high levels of borrelial IgG antibodies, slowly expanding skin redness usually beginning on distal parts of extremities, and corresponding histologic findings. It very rarely develops in children. The main prerequisite for the diagnosis is clinical suspicion. In the present article we report on two children with acrodermatitis chronica atrophicans and on the findings of a PubMed literature search on acrodermatitis chronica atrophicans in childhood, published in the past three decades.

Keywords: Acrodermatitis chronica atrophicans; Borrelia afzelii; Childhood; Late Lyme borreliosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acrodermatitis / diagnosis*
  • Acrodermatitis / drug therapy
  • Acrodermatitis / microbiology
  • Administration, Intravenous
  • Adolescent
  • Borrelia / immunology*
  • Borrelia / isolation & purification
  • Ceftriaxone / therapeutic use*
  • Child
  • Female
  • Humans
  • Lyme Disease / diagnosis*
  • Lyme Disease / drug therapy
  • Lyme Disease / microbiology
  • Lyme Disease / pathology
  • Skin / microbiology
  • Skin / pathology
  • Treatment Outcome

Substances

  • Ceftriaxone