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Am J Dis Child. 1987 Jun;141(6):698-700.

Hepatocarcinoma in a child with the Alagille syndrome.

Abstract

A child with the Alagille syndrome of intrahepatic bile duct paucity developed hepatocarcinoma. Disabling cirrhosis had rendered this child a suitable candidate for transplantation before the discovery of carcinoma. However, the extension of the tumor outside the liver precluded the performance of this potentially life-saving operation. Serial monitoring of the serum alpha-fetoprotein concentration may be of value in the early identification of tumors in pediatric candidates for transplantation.

PMID:
3034054
[PubMed - indexed for MEDLINE]
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