A tent pole twist on membrane ruffles

J Cell Biol. 2018 Nov 5;217(11):3774-3775. doi: 10.1083/jcb.201810022. Epub 2018 Oct 10.

Abstract

Macropinocytosis or "cell drinking" involves the elaboration of membrane ruffles that enclose and internalize extracellular fluids. Using lattice light sheet microscopy, Condon et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201804137) reveal the presence of parallel membrane protrusions termed "tent poles" that flank and direct membrane ruffle formation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Cell Membrane Structures*
  • Endosomes*
  • Macrophages
  • Membranes
  • Pinocytosis