Cancer Lett. 1977 Sep;3(3-4):121-4.

Specific attachment of T-lymphocytes from cancer patients to tumor cells.

Galili U, Caine M, Servadio C, Schlesinger M.

Abstract

The present study describes a new approach for detecting the immune reaction of peripheral blood lymphocytes of cancer patients against tumor antigens. T-lymphocytes from patients with carcinoma of the urinary bladder were found to attach specifically to monolayers of cells of urinary bladder carcinoma line (T24). The attached T-cells were identified by their capacity to form E-rosettes with sheep red blood cells. The number of rosette forming--target attached lymphocytes (RF--TAL) was 6 times higher in bladder carcinoma patients than in healthy controls or in patients bearing other types of cancer.

PMID:: 302735; [PubMed - indexed for MEDLINE]

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Antigens, Neoplasm

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Specific attachment of T-lymphocytes from cancer patients to tumor cells.

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Medical

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Cited by 1 PubMed Central article

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