Pulmonary Extraintestinal Manifestation of Crohn's Disease Treated Successfully with Adalimumab

Korean J Gastroenterol. 2018 Sep 25;72(3):141-145. doi: 10.4166/kjg.2018.72.3.141.

Abstract

Pulmonary extraintestinal manifestation is rare in Crohn's disease and has been reported in only a few cases. Despite the presence of pulmonary abnormalities in a significant proportion of patients with inflammatory bowel disease, there are only few case reports, due to complicated diagnosis and low recognition by clinicians. Currently, treatment guidelines for pulmonary Crohn's disease have not been established. There are some case reports of pulmonary Crohn's disease that achieved remission after infliximab treatment. Clinical and radiological remission of pulmonary extraintestinal involvement in Crohn's disease after adalimumab therapy has not been reported yet. Here, we report one case of lung involvement of Crohn's disease, which shows radiological and clinical remission after adalimumab treatment.

Keywords: Crohn disease; Extraintestinal manifestation; Inflammatory bowel diseases; Multiple pulmonary nodules.

Publication types

  • Case Reports

MeSH terms

  • Adalimumab / therapeutic use*
  • Adult
  • Anti-Inflammatory Agents / therapeutic use*
  • Colonoscopy
  • Crohn Disease / drug therapy*
  • Female
  • Humans
  • Necrosis
  • Positron Emission Tomography Computed Tomography
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents
  • Adalimumab