[MORPHOMETRIC ANALYSIS IN THE ZONE OF CONTACT OF VARIOUS TYPES OF IMPLANTS AND TISSUE OF KIDNEYS OF THE RATS EARLY TIME EXPERIMENT]

Georgian Med News. 2018 Jul-Aug:(280-281):129-134.
[Article in Russian]

Abstract

To this day, limiting the amount of sampling of donor tissue and organs, tissue rejection issues and numerous possible complications remain unresolved problems and are an actual problem of practical urology. This provision indicates the existence of a need to find alternative methods for solving this problem. The aim of the study was to study and compare the morphometric values of various types of implants with the tissue of the kidneys of rats in the early periods. The object of a comparative experimental study was decellularized bovine - derived tissue and a macroporous partially absorbable light UltraPro mesh. The experimental subjects were 48 white non-linear short-haired sexually mature rats of both sexes weighing 180-220 g. The autopsy days of experiment on 7 day, x 21 day sand 30 days. The micropreparations are colored with hematoxylin and eosin. The decellularized bovine - derived tissue absence inflammatory and destructive changes in the implantation zone, compared by the mesh UltraPro. Consequently .these results in the study groups indicate that the implants are biocompatible and do not generate the manifest forms of the heperergic immune response in the rat tissue, since they absence persistence and progression of the exudative reaction.

MeSH terms

  • Animals
  • Biocompatible Materials* / toxicity
  • Cattle
  • Female
  • Implants, Experimental*
  • Kidney / blood supply
  • Kidney / immunology
  • Kidney / pathology*
  • Male
  • Rats
  • Surgical Mesh / adverse effects

Substances

  • Biocompatible Materials