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Hum Genet. 1986 Aug;73(4):320-6.

A routine method for the establishment of permanent growing lymphoblastoid cell lines.


Permanent lymphoblastoid cell lines are of great practical value in human clinical and experimental genetics. A detailed protocol for routine use is given for the establishment of lymphoblastoid lines from peripheral blood using Epstein-Barr virus and the immunosuppressivum Cyclosporin A. In addition, the biologic basis of this transformation system is briefly summarized.

[PubMed - indexed for MEDLINE]
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