[Clinical, pathological and microbiological association of Helicobacter pylori in gastric biopsies in the department of Caldas-Colombia]

Rev Gastroenterol Peru. 2018 Apr-Jun;38(2):144-150.
[Article in Spanish]

Abstract

Objective: To establish the clinical, pathological and microbiological association of Helicobacter pylori in gastric biopsies in a population of the department of Caldas (Colombia).

Materials and methods: We included 72 patients, who were referred for digestive endoscopy to the San Marcel clinic in the city of Manizales during the second half of 2015; two biopsies of the antrum and two of the body of the stomach were taken for histopathological study and microbiological culture. Data were submitted to descriptive and relational statistical procedures.

Results: H. pylori was found in 47.2% by histological analysis and 26.4% by microbiological culture, with predominance in the female sex. Epigastralgia is the main reason for consultation associated with H. pylori infection.

Conclusion: we found an association between the reason for consultation, female sex, microbiological culture and histological presence of H. pylori. Age was associated with established endoscopic diagnosis. The culture presented a high specificity (84.2%) and a low sensitivity (38.2%), compared to the histopathological finding.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Biopsy
  • Colombia / epidemiology
  • Female
  • Helicobacter Infections / diagnosis*
  • Helicobacter Infections / epidemiology
  • Helicobacter Infections / pathology
  • Helicobacter pylori / isolation & purification*
  • Humans
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Stomach / microbiology*
  • Stomach / pathology*
  • Young Adult