Myristylation of gag protein in human T-cell leukemia virus type-I and type-II

Jpn J Cancer Res. 1985 Dec;76(12):1132-5.

Abstract

We found that p19gag of HTLV-I and p23gag of HTLV-II are myristylated. The p28, which is immunologically cross-reactive with monoclonal antibody against p19gag of HTLV-I was also shown to be myristylated in the HTLV-I-infected cell lines MT-2 and HUT102. However, no myristylated p28 was found in HTLV-II-infected cell lines, Mo and Ton1.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal
  • Deltaretrovirus / metabolism*
  • Gene Products, gag
  • Myristates / metabolism*
  • Myristic Acids / metabolism*
  • Palmitates / metabolism
  • Protein Processing, Post-Translational
  • Retroviridae Proteins / metabolism*

Substances

  • Antibodies, Monoclonal
  • Gene Products, gag
  • Myristates
  • Myristic Acids
  • Palmitates
  • Retroviridae Proteins