Advances in Glioblastoma Operative Techniques

Evan D Bander; Rajiv Magge; Rohan Ramakrishna

doi:10.1016/j.wneu.2018.04.023

Advances in Glioblastoma Operative Techniques

World Neurosurg. 2018 Aug:116:529-538. doi: 10.1016/j.wneu.2018.04.023.

Authors

Evan D Bander¹, Rajiv Magge², Rohan Ramakrishna³

Affiliations

¹ Department of Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA.
² Department of Neurology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA.
³ Department of Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA. Electronic address: Ror9068@med.cornell.edu.

PMID: 30049047
DOI: 10.1016/j.wneu.2018.04.023

Abstract

Numerous studies have demonstrated the importance of gross total resection in improving patient survival in glioblastoma (GBM). Advances in surgical tools and techniques such as intra-operative imaging, fluorescent agents, and functional imaging sequences are allowing for better identification of tumor borders and vital eloquent cortex in order to safely achieve higher rates of complete resections. Furthermore, due to the limits of surgical resection alone, new minimally invasive techniques for treatment of GBM are under development. These advances are crucial for improving neurosurgical care and outcomes in this difficult patient population.

Keywords: 5-ALA; Convection-enhanced delivery; Extent of resection; Functional neuronavigation; Glioblastoma; Intraoperative MRI; Ultrasound.

MeSH terms

Brain Neoplasms / surgery*
Glioblastoma / surgery*
Humans
Monitoring, Intraoperative* / methods
Neuronavigation* / methods
Neurosurgical Procedures* / methods
Ultrasonography / methods