Nucleic Acids Res. 1985 Dec 20;13(24):8827-41.

Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens.

Abstract

The primary structures of a cDNA and the genomic DNA of a gene selectively expressed in chronic lymphocytic leukemia were determined. A computer search of the nucleotide sequence data bank identified this gene as the invariant gamma-chain associated with class II histocompatibility antigens. The invariant gamma-chain genomic sequence spans about 11 kilobases, with eight exons and seven introns. Three of the introns contain members of the Alu repeat family. A putative cap site and promoter sequence were identified at the 5' end of the gene. One or two copies of the gene is present in each haploid genome, and no evidence for amplification or polymorphism was obtained.

PMID:: 3001652; [PubMed - indexed for MEDLINE]
PMCID:: PMC318954

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Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes. [Proc Natl Acad Sci U S A. 1986]
Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.
O'Sullivan DM, Larhammar D, Wilson MC, Peterson PA, Quaranta V. Proc Natl Acad Sci U S A. 1986 Jun; 83(12):4484-8.
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Cited by 12 PubMed Central articles

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Brown AM, Linhoff MW, Stein B, Wright KL, Baldwin AS Jr, Basta PV, Ting JP. Mol Cell Biol. 1994 May; 14(5):2926-35.
Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes. [Proc Natl Acad Sci U S A. 1986]
Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.
O'Sullivan DM, Larhammar D, Wilson MC, Peterson PA, Quaranta V. Proc Natl Acad Sci U S A. 1986 Jun; 83(12):4484-8.

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Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens.
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